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education
Breast cancer screening and MRI usage
The American Cancer Society
recently released updated breast cancer screening guidelines that talk about
the use of magnetic resonance imaging (MRI). This change marks the first
time in four years that the Society has updated its recommendations on the
early detection of breast cancer.
What
does this mean for women seeking mammograms?
Mammography is highly
effective in detecting breast cancer at an early stage and, when followed up with
appropriate diagnosis and treatment, reducing mortality from breast cancer.
For women at an increased risk of breast cancer, other screening
technologies also may contribute to the earlier detection of breast cancer.
The Society recommends the
addition of MRI screening to mammography for women at high risk of breast
cancer, which includes those who:
-
have a
known BRCA1 or BRCA2 gene mutation
-
have a
first-degree relative (mother, father, brother, sister, or child) with a
BRCA1 or BRCA2 gene mutation, and have not had genetic testing themselves
-
have a
lifetime risk of breast cancer of 20%-25% or greater, according to risk
assessment tools that are based mainly on family history
-
had
radiation therapy to the chest when they were between the ages of 10 and
30 years
-
have
Li-Fraumeni syndrome, Cowden syndrome, or Bannayan-Riley-Ruvalcaba
syndrome, or have one of these syndromes in first-degree relatives
It is
also recommended that women at moderately increased risk talk with their
doctors about the benefits and limitations of adding MRI screening to their
yearly mammogram. Women at moderately increased risk include those who:
-
have a
lifetime risk of breast cancer of 15%-20%, according to risk assessment
tools that are based mainly on family history
-
have a
personal history of breast cancer, ductal carcinoma in situ (DCIS),
lobular carcinoma in situ (LCIS), atypical ductal hyperplasia (ADH), or
atypical lobular hyperplasia (ALH)
-
have
extremely dense breasts or unevenly dense breasts when viewed by
mammograms
While
MRI is more sensitive in detecting cancers than mammograms, it also has a
higher false-positive rate (where the test finds something that turns out
not to be cancer), which results in more recalls and biopsies. This is why
it is not recommended as a screening test for women at average risk of
breast cancer, as it would result in unneeded biopsies and other tests in a
large portion of these women.
The use of regular mammograms, MRI (in women at high risk), clinical breast
exams, and finding and reporting breast changes early offers women the best
opportunity for reducing the breast cancer death rate through early
detection. This combined approach is clearly better than any one test for
early detection.
If
you are a woman who is 40 or older, remember to schedule your yearly
mammogram. For more information about the American Cancer Society’s
screening guidelines, visit
www.cancer.org or call 1-800-ACS-2345 anytime,
day or night. No matter who you are, we can help.
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